Malaysian Nasal Polyps: Eosinophil or Neutrophil-Predominant
Malaysian Nasal Polyps
Vol. 11 No. 1 : 2016 (56-61)
Abstract
Eosinophil-type nasal polyp (NP) is common in Western population. This aim of this study was to determine the histology type of NP among different Malaysian ethnic groups. A total of 122 chronic rhinosinusitis with nasal polyposis (CRSwNP) patients were retrospectively enrolled and demographic data was recorded. The histological slides were retrieved. The number of eosinophils and non-eosinophils were counted and average number of inflammatory cells for each high power field was calculated. Eosinophil-predominant was seen in 32.8% of patients and 67.2% was non-eosinophil-predominant. Phenotypes of NP significantly showed an association with ethnicity (x² = 8.322; p < 0.05). A total of 78.9% of Chinese nasal polyps showed non-eosinophil predominant, while Malay and Indian nasal polyps revealed 71.9% and 40.7% of non-eosinophilic phenotype, respectively. Our study showed that Malaysian population had a non-eosinophilic phenotype of nasal polyps. There was a significant association in Malaysian ethnicity with the highest percentage in Chinese population.
Keywords :
eosinophil,
histology,
polyps,
Correspondance Address
Salina Husain, Department of Otorhinolaryngology-Head and Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia. Tel: +60391456045 Fax: +60391456675 Email: drsalina_h@yahoo.com
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