Quantitative Ultrasound (QUS) for the Assessment of Bone Health

Quantitative Ultrasound (QUS) and Bone Assessment
Vol. 9 No. 1 : 2014 (1-10)

Aqilah-SN SMZ Aqilah-SN SMZ
ZULFARINA SM ZULFARINA SM
Nazrun AS Nazrun AS
SABARUL AM SABARUL AM
Isa NM Isa NM

Abstract
Osteoporosis is known as a silent disease because bone density slowly decreases with advancing age and without symptoms. The incidence of osteoporosis is increasing yearly worldwide. Measuring bone mineral density (BMD) using conventional bone densitometry (DXA) is practical in diagnosis of osteoporosis but the cost is high and cannot be implemented in community. However, quantitative ultrasound (QUS) is a modern technique to measure the bone density and also for the diagnosis of osteoporosis. It is comparatively easy, reliable, less costly, and a safe method compared to other techniques. QUS consists of two main parameters which are known as broadband ultrasound attenuation (BUA) and speed of sound (SOS). QUS can also predict fracture risk of BMD. QUS showed significantly associated with BMD, bone micro architecture and mechanical parameters for In vitro studies and in human studies, QUS were found to be associated with BMD. Hence, QUS is capable to be new technique for bone assessment.

Keywords : Bone Density, Dual Energy X-Ray (DXA), osteoporosis, Quantitative Ultrasounds (QUS),

Correspondance Address
Siti Zulfarina Mohamed, Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaacob Latif, Bandar Tun Razak, 56000 Cheras, Kuala Lumpur, Malaysia. Tel: 03-91459547 Fax: 03-91459547 Email: szulfarinamohamed@gmail.com


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